Rad4/Cut5 is a scaffold protein in the Chk1-mediated DNA damage checkpoint in S.pombe.However, whether it contains a robust ATR-activation domain (AAD) required for checkpoint signaling like its orthologs TopBP1 in humans and Dpb11 in budding yeast has been incompletely clear.To identify the putative AAD in Rad4, we carried out an extensive genetic
Bipedalism is the main characteristic of humans.During evolutin bipedalism emerged probably as an adaptation to a changing environment.Major changes in skeletal system included femur, CLEANSE pelvis, skull and spine.The significance of bipedal locomotion: Bipedalism freed the forelimbs for carrying objects, creation and usage of tools.In the uprigh
The SENNA LEAVES study of medieval notations depends on effective categorization of individual signs in order to facilitate a comprehensive understanding of their musical meaning.Over the past century, chant scholars have developed several kinds of neume tables which arrange and contextualize neumes either according to graphical type, chronology, o
This article explores motion comics through theoretical review of relevant academic work and unique analysis of three sampled motion comic cases.The article intends to Sanding Accessories illuminate and answer the research question: What is the quality of superhero motion comics if we consider both the medium aesthetics and the opportunities which